2015 - Volume 2 - Issue 1 Articles
-
Short Communication | ArticleBy Tatsuya Kurihara Hirotaka Katoh Ken-ichi Saguchi Masakazu Ishii Mitsuru Kawamura Shunichi ShimizuJanuary 29, 2015 | Pages : 205 - 450Abstract We here in investigated whether dopamine-related gene polymorphisms were involved in the aggravation of migraines due to the overuse of medication. Polymorphisms in the catechol-O methyltransferase (COMT, rs4680, rs2075507), dopamine-? hydroxylase (D.....
-
Short Communication | ArticleBy Shunya Goto Ataru Uehara Dai Kato Katsuya Niki Masashi Fukuoka Masaya Ohtsu Shu-ichiro Kashiwaba Yasufumi MurakamiJuly 13, 2015 | Pages : 205 - 450Abstract In mammalian cells, transcription is globally silenced during mitosis owing to the highly-condensed chromatin. Immediately after mitosis, daughter cells restart the transcription of early G1 genes along the program which is transmitted from parental .....
-
Short Communication | ArticleJune 27, 2015 | Pages : 205 - 450Abstract The human genetic disorder, Neurofibromatosis Type 1 (NF1), by virtue of its wellstudied variability and complexity, presents a compelling opportunity to examine the relationships of genotypes and phenotypes in general. A new concept, the praxitype, .....
-
Short Communication | ArticleBy Alfons Meindl Claus Lenski Heiner Schaal Jan Otto Peter Juliane Ramser Marek Widera Steffen ErkelenzNovember 11, 2015 | Pages : 205 - 450Abstract Previously, we associated two mutations with the diseases X-linked congenital spinal muscular atrophy (SMAX2) and a syndromic form of X-linked mental retardation (MRXS10). These mutations are synonymous, meaning that they do not influence the amino a.....